Kaecilius uses the stolen pages to contact Dormammu of the Dark Dimension, where time is non-existent. Mordo and Wong warn Strange against breaking the laws of nature, drawing a comparison to Kaecilius' desire for eternal life. Strange progresses quickly, and secretly reads the text from which Kaecilius stole pages, learning to bend time with the mystical Eye of Agamotto. The sorcerers' task is to protect the Sanctums, though Pangborn instead chose to channel mystical energy only into walking again. Strange learns that Earth is protected from threats from other dimensions by a shield generated from three buildings called Sanctums, in New York City, London, and Hong Kong, which are all directly accessible from Kamar-Taj. Strange studies under the Ancient One and Mordo, and from ancient books in the library that is now guarded by Master Wong. She reluctantly agrees to train Strange, whose arrogance and ambition remind her of Kaecilius. The Ancient One demonstrates her power to Strange, revealing the astral plane and other dimensions such as the Mirror Dimension. Pangborn directs Strange to Kamar-Taj, where he is taken in by Mordo, a sorcerer under the Ancient One. Strange learns about Jonathan Pangborn, a paraplegic who mysteriously regained use of his legs. Fellow surgeon Christine Palmer tries to help him move on, but Strange vainly pursues experimental surgeries to heal his hands. Stephen Strange, a wealthy, acclaimed, and arrogant neurosurgeon, severely injures his hands in a car crash while en route to a speaking conference, leaving him permanently unable to operate. The Ancient One pursues the traitors, but Kaecilius and his followers escape. They steal several pages from an ancient, mystical text belonging to the Ancient One, a long-lived sorcerer who has taught every student at Kamar-Taj, including Kaecilius, in the mystic arts. In Kathmandu, the sorcerer Kaecilius and his zealots enter the secret compound Kamar-Taj and behead its librarian.

A sequel, Doctor Strange in the Multiverse of Madness, was released in May 2022. The film received an Academy Award nomination for Best Visual Effects. The film grossed over $677 million worldwide and was met with praise for its cast, visual effects, and musical score. Principal photography on the film began in November 2015 in Nepal, before moving to England and Hong Kong, and wrapping up in New York City in April 2016.Дoctor Strange had its world premiere in Hong Kong on October 13, 2016, and was released in the United States on November 4, as part of Phase Three of the MCU. This gave Derrickson time to work on the script himself, for which he brought Cargill on to help. Cumberbatch was chosen for the eponymous role in December 2014, necessitating a schedule change to work around his other commitments. In June 2014, Derrickson was hired to direct, with Spaihts re-writing the script. Thomas Dean Donnelly and Joshua Oppenheimer were brought on board in June 2010 to write a screenplay. Various incarnations of a Doctor Strange film adaptation had been in development since the mid-1980s, until Paramount Pictures acquired the film rights in April 2005 on behalf of Marvel Studios.

In the film, Strange learns the mystic arts after a career-ending car crash. Robert Cargill, and stars Benedict Cumberbatch as neurosurgeon Stephen Strange along with Chiwetel Ejiofor, Rachel McAdams, Benedict Wong, Michael Stuhlbarg, Benjamin Bratt, Scott Adkins, Mads Mikkelsen, and Tilda Swinton. The film was directed by Scott Derrickson from a screenplay he wrote with Jon Spaihts and C. Produced by Marvel Studios and distributed by Walt Disney Studios Motion Pictures, it is the 14th film in the Marvel Cinematic Universe (MCU). Doctor Strange is a 2016 American superhero film based on the Marvel Comics character of the same name.

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